IgG Avidity ELISA Test for Diagnosis of congenital toxoplasmosis

Toxoplasmosis is a parasitic disease which may cause some laboratory symptoms in infected individuals. One of the main ways to transmit this organism is placenta to fetus pathway. If this transmission occur in the third month of pregnancy the abortion, central nerve system and ocular disorders will happen. Because of this issue, precise techniques such as ELISA & ELISA Avidity for detection of Toxoplasma Antibody (IgG and IgM) are important. The aim of this study was to detect the time of infection of mothers with toxoplasma gondii. The study method was evaluation assessment. In this survey, the main samples are serum and amniotic fluid that was collected from 48 pregnant women infected with toxoplasma gondii in Shariaty hospital. The statistical method was based on spss18 software. The results of this survey showed that, in these pregnant women the infection of toxoplasma gondii is occurred and many of them are infected currently and in both samples the mean of ELISA avidity titer elevated that was associated with number of abortion. In simple ELISA technique, the only antibody which can be detected precisely is IgM; but in this technique the IgG antibody is also detected. In this recent technique or ELISA AVIDITY, in addition to detection of IgG antibody against toxoplasma gondii, the month of transmission of toxoplasma is interpreted.