Effects of Aerobic Training, with or without Zizyphus Jujuba Water Extraction, on Fundus Nesfatin-1, ATP, HDL-C, and LDL-C Concentrations in Female Rats

The aim of this study was to investigate the effects of six weeks of aerobic training, with and without extract of Jujuba, on fundus nesfatin-1, ATP concentration, plasma High-density lipoprotein (HDL), and Low-density lipoprotein (LDL) levels in female rats. 28 Wistar rats were randomly assigned to Saline-control, Saline-training, Jujuba-control and Jujuba-training groups. Training groups were given exercise on a motor-driven treadmill at 35 m/min (0% grade) for 60 min/day and 5 days/week for six weeks. Animals were fed orally, with Jujuba extraction and Saline (3 weeks, 60 mg per 100 g body weight). 72 hours after the last training session and after four hours of fasting, the rats were sacrificed, and their fundus tissue was excised. Some plasma was also collected for plasma variable measurements. All variables were compared using one way analyzes of variances. Correlations were calculated using the Pearson Product Moment correlation. All P values