Comparison of acute responses of blood coagulation system in active and inactive men

The aim of this study was to investigate the effect of acute exercise on platelet and coagulation system in active and inactive men. Fifteen physically inactive men (24.9 ± 1.37 years) and 15 regularly active men (25.6 ± 1.34 years) performed sub-maximal (70% VO2 max) exercise trial for 30 min. Platelet count(PC), fibrinogen, Activated partial thromboplastin time(aPTT) and Prothrombin time(PT) were measured before, immediately after exercise, and after 30 minutes recovery. 30 min exercise training resulted in significant decrease in PT and aPTT (P<0.001). Partial eta2 results, also indicated that 0.712 and 0.737 of PT and aPTT changes, respectively, accounted for the exercise training (P<0.001). It was concluded that it seems that physical exertion increases PC, and also stimulates coagulation system, that may increase the risk for arterial thrombogenesis, especially in inactive subjects.