In-Vitro Effect of Hydro-Alcoholic Extract of Tanacetum Parthenium Extract on Trichomonas Vaginalis

Trichomonas vaginalisis a flagellate parasite causing vaginosis as a common sexual transmitted disease. Metronidazole is the drug of choice for this disease; but due to its side effects it is necessary to search for an alternative drug. In this study، the effect of Tanacetum parthenium on Trichomonas vaginalis was investigated.

Using percolation method، hydro-alcoholic extracts of Tanacetum parthenium was prepared. The extract was dried using vacuum rotary evaporator. Different doses of the extract were added to 8 tubes containing culture medium of Trichomonas vaginalis; metronidazole was added to 1 tube. Finally، 104 Trichomonas vaginalis was added to each tube. Every 24 hours for 3 days، the tubes were seen for count and motion of the parasite under the microscope.

In concentrations of 4، 5، 8 and 10 mg/ml of Tanacetum parthenium، the parasite did not grow. The effect of the extract on Trichomonas vaginalis was similar to the effect of metronidazole.

Tanacetum parthenium has efficient effect against Trichomonas vaginalis growth in culture medium; so، this herb can be considered as alternative drug for methronidazole.