Effect of acute exercise on fibrinolytic responses of judokas in the different times of day

The aim of this study was to compare fibrinolytic responses of judokas to submaximal aerobic exercise in the different times of day. Fifteen judokas aged 24.9 ± 1.37 (mean ± SD) years performed two exercise sessions, morning and evening, at 70% of maximal oxygen consumption (VO2max) on cycle ergometer for 30 min. The venous blood samples have been drawn at rest, immediately post exercise and after 30 min of recovery period for measure tissue plasminogen activator (tPA) and plasminogen activator inhibitor-1 (PAI-1) activity. Exercise presented significant increases in tPA activity (P≤ 0.001), which returned to the baseline values after recovery in both exercises. PAI-1 activity no longer demonstrated exercise-related changes (P˃ 0.05), but it was significantly higher during the morning than evening sessions (P≤ 0.05). The results of present study demonstrated that exercise resulted in activation fibrinolytic system. But during recovery, fibrinolytic activity decreased quickly to the baseline values. In addition, the time of day plays an important role in exercise-induced fibrinolytic changes.