The Effect of Interval Training on Tumor Volume in Mice with Carcinoma Tumor
Author(s):
Abstract:
Introduction
Exercise has effects on changing cancer factors, yet the effect of exercise on the levels of cancer factors in inflicted animals or humans has not been seriously paid attention to. Thus the aim of this study is to study the effect of aerobic continuous training on tumor volume on mice with carcinoma.Methods
In this study, 30 female balb/c mice were selected and after transplanting adenocarcinoma tumor in peritoneal area, the mice were randomly divided into a tumor-control and interval training-tumor groups. Interval training protocol was done for 7 weeks at 20% vo2max in the first week and 75% vo2max in the last week. Speleenectomy where doneafter interval training protocol, and Eliza method used to measure Heat Shock Protein 70 (HSP70), Interleukin 4 (IL4) and Interferon γ (IFNγ).Results
The results of this study showed a decrease in the amount of Hsp70 in interval training group but the difference between the two groups was not significant (P>0.05). The results also showed a decrease in the levels of IL4 in the interval training-tumor group but there was no significant difference between the groups (P>0.05). The levels of IFN in interval training-tumor group were higher than those of the control group but this difference was not significant either (P>0.05). However, tumor mass in interval training-tumor group significantly decreased (P=0.001).Conclusion
Based on the results of this research, it can be concluded that doing interval training through changing the amount of effective factors on cancer can lead to a decrease in volume mass.Keywords:
Interval training , Tumor mass , Hsp70 , IL4 , IFNγ
Language:
Persian
Published:
Journal of Knowledge & Health, Volume:8 Issue: 4, 2013
Page:
144
magiran.com/p1209902
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!