Analgesic Effect of Rectal Indomethacin on Pain after Cesarean Section

Cesarean section is one of the most common women surgeries. Post surgical pain leads to delay in successful initiation of breastfeeding and pain relief accelerates the communication between mother and newborn. The aim of this study was to evaluate the analgesic effect of rectal indomethacin suppository on pain relief after cesarean section. This prospective double blind randomized clinical trial was conducted on 65 term pregnant women who referred to Omolbanin hospital، Mashhad، Iran in 2011 for elective cesarean section. Rectal indomethacin suppository and placebo were described before anesthesia for 35 and 30 cases، respectively. Pain score was measured in both groups، 3 and 24 hours after cesarean using visual analogue scale. Data were analyzed using SPSS software (version 16)، chi-square and t-student tests. P value less than 0. 05 was considered significant. Demographic characteristics were same in two groups. Mean duration of surgery was 108±45 minutes. Gas passing in first 24 hours was significantly higher in indomethacin group (p=0. 035). The mean of post operative pain did not show significant differences between two groups. (p>0. 05) Indomethacin might reduce post operative pain at 3 and 24 hour after cesarean section but this is not significant. Therefore، the use of rectal indomethacin suppository before cesarean section was not effective for pain relief in this study.