Comparison of Results of DNA Detection of Helicobacter Pylori, Chlamydia Pneumoniae and Mycoplasma Pneumoniae in Patients Undergoing Emergency and Elective Abdominal Aortic Aneurysm Surgery

Introduction & The thirteenth most common cause of death in the Western world is ruptured abdominal aortic aneurysm. Although considerable researches have been done about to the etiology and mechanism of aneurysm expansion، little is known about the mechanism of rupture. The aim of this study was to evaluate the possible role of helicobacterpylori and chlamydia pneumoniae and mycoplasma pneumoniae in the expansion and rupture of abdominal aorta aneurysm. In this cross sectional study، we evaluated 50 patients with abdominal aorta aneurysm، in a period of 2 years at our hospital. Four patients with a history of dyspepsia and anti-Helicobacter pylori therapy or a recent history of upper respiratory infection were excluded from our study. Patients were divided into two groups، based on the indication for aneurysm surgery. The first group had undergone elective abdominal aortic aneurysm surgery and the second group had undergone emergency surgery of ruptured aortic aneurysm. During surgery، was performed sampling of the aneurysm wall was done. Samples were immediately transported to the laboratory to have the extraction of DNA of microbes by PCR. In this study، 46 patients were evaluated. In both groups، helicobacterpylori DNA and mycoplasma pneumoniae DNA weren’t detected. But the highest rates of Chlamydia pneumoniae DNA was detected in patients with ruptured abdominal aortic aneurysm (P