Comparison of QT Dispersion Alterations in ST-ElevationMyocardial Infarction Patients Undergoing Thrombolytic Therapy versus Primary PCI

We compared QT dispersion alterations between the two methods of thrombolytic therapy and primary percutaneous coronary intervention (PCI) in patients with ST elevation myocardial infarction (STEMI). Methods and In this cohort, STEMI in patients who underwent thrombolytic therapy (n=63) and those who underwent primary PCI (n=63) was assessed and QT dispersion was recorded at admission and after two days for a comparison of the total reduction. The mean QT dispersion reduction was 0.0092 and 0.0049 in the thrombolytic therapy and PCI groups, respectively, showing a significant difference (P = 0.001). The mean change in QT dispersion in women was significantly higher than that in men (P = 0.01). Patients with anterior MI had a significantly longer QT dispersion (P = 0.02). There was a significant linear reverse association between QT dispersion and ejection fraction (P < 0.05). In our STEMI patients, QT dispersion after PCI and thrombolytic therapy was significantly decreased. The reduction was more significant in PCI, demonstrating the higher efficacy of PCI for reperfusion. (Iranian Heart Journal 2014; 15(3): 6-11)