The Association between Serum Ferritin and Iron Parameters with Preeclampsia

Background and High blood pressure is a common complication of pregnancy which is responsible for maternal morbidity and mortality. In some studies، abnormality in iron parameters has been reported in preeclampsia. Also، increased serum ferritin levels (that reflect body iron status) early in preeclampsia compared with normal pregnancy have been reported. Some researches، however، indicated different results. This case-control study was performed in pregnant women attending prenatal care unit and hospital maternity at Imam Khomeini Hospital in Sari. We evaluated serum iron indices and hematological parameters such as hemoglobin and hematocrit concentrations in patients with preeclampsia and compared them with those of the women having normal pregnancies. There were significant differences in serum iron and ferritin levels in women with preeclampsia compared with those of the women with normal pregnancies، 113. 87 vs 73. 23، 63. 8 vs 22. 47، respectively. Also، TIBC level was significantly lower in preeclamptic women. No significant differences were found between the two groups in RBC count، hematocrit and hemoglobin values. According to this study، it is believed that iron profile including iron and ferritin serum levels، and transferrin saturation is higher in women with preeclampsia.