The effects of a combined aerobic and resistance exercise training on GFR and serum factors of renal function in men with type 2 diabetes

The aim of this research was to effects of a combined resistance and aerobic exercise program on Glomerular Filtration Rate (GFR) and Biochemical factors serum levels relationship with renal function in type II diabetic patients. 20 patients with type two diabetes (mean age 52. 73 years، mean weight 82 kg، mean BMI 30. 51 kg/m2، mean FBS 155. 92 mg/dl) were randomly assigned to either an experimental group (N=10) or a control group (N=10). The experimental group performed thrice a week for 10 weeks of aerobic and resistance training and control group continued with their usual activities. For measuring Urea (BUN)، Creatinin (Cr) and Uric Acid (UAc) serum levels and Glomerular Filtration Rate، blood samples were obtained in 2 stages، weeks zero and ten. T-student and paired T-tests was used to compare before and after exercise training between groups. Statistical significance was assumed at P ≤ 0. 05. Blood Urea (BUN) and Creatinin (Cr) and Glomerular Filtration Rate was significantly decreased in experimental group (P≤ 0. 05); whereas this difference in these factors in control group was not significant. The Uric Acid (UAc) factor serum level in two groups was not significant. The findings of this research showed that combined resistance and aerobic exercise training causes a significant improvement in Glomerular Filtration Rate and Urea (BUN) and Creatinin (Cr) serum level in patients with type II diabetes.