Mole Incidence in Hamadan Province of Iran

Gestational trophoblastic disease includes a group of tumors such as complete and partial hydatidiform mole، choriocarcinoma and placental trophoblastic tumor. Epidemiology of the disease is unknown. This study was performed with aim to determine the incidence of mole in Hamadan province of Iran during 1997 to 2006. This retrospective descriptive study was conducted on the records of 292262 pregnant women referred to medical centers and clinics of labor facilities in Hamadan Province during 1997 to 2006. The data collection tool was a questionnaire. Data were analyzed using SPSS software (version 13). The incidence of hydatidiform mole in Hamadan Province during 1997 to 2006 was 3. 34 per 1000 pregnancy and 3. 7 per 1000 delivery. 533 patients (56. 1%) had complete mole. The highest incidence of molar pregnancy (68. 8%) was seen in the age range group of 21-35 years. The incidence of mole recurrence was 2. 6%. In comparison of gravidity، most cases of molar pregnancy was related to gravidity 1 that its relationship with the incidence of mole was significant (P=0. 002) and also، there was a significant relationship between the history of molar pregnancy with incidence of mole (P=0. 032). In the Hamadan province like as parts of Southeast Asia، there is a high incidence of mole، so the early diagnosis of the disease must be considered.