Case report: Follow-up, diagnosis, clinical evidence, laboratory evaluation, and treatment of Idiopathic thrombocytopenia using human Intravenous Immunglobulin in a terrier dog

The aim of the present case report is to describe the outcome, hematological and biochemical changes of treatment of idiopathic thrombocytopenia in a Terrier dog using human intravenous immunglobulin. The complete blood count, serum biochemistry, indirect immunofluorescence antibody and direct coomb’s tests, radiography and sonography were performed. Laboratory findings indicated sever thrombocytopenia (<15×103/μl) and mild leukocytosis. Increase in the erythrocyte sedimentation rate and total protein concentration were last up to 19 and 14 days, respectively. After it, areduction was observed and no relapse was reported. This case report provides the first successful treatment and clinical evidence of a terrier dog with idiopathic thrombocytopenia in which no underlying etiology has been identified. It was concluded that human intravenous immunoglobulin infusion (1 g/kg) is a safe treatment with a significant increase in platelet count without increase in hospitalization and the cost of patient care.