Assessment of relationship between body mass index i and serum levels of prostate specific antigen in 40-79 year old men referred to Rasoul Akram hospital

The level of Prostate-Specific Antigen (PSA) in identifying patients at high risk for prostate cancer has always been a controversial issue. This study was designed in order to assess the relationship between PSA levels with age and Body Mass Index (BMI) in symptom free men. In this cross sectional study، demographic data and PSA levels in 180 men referred to Rasoul Akram Hospital with analysis، data description، chi-square and correlation tests with SPSS software were used. The mean age of men was 60. 7±9 years and the mean of BMI was 26. 1±3. 5 kg/m2. This study showed inverse correlation between PSA and BMI which was very low and insignificant (p=0. 141). But the correlation between PSA and age were significant and positive. This study showed there is no correlation between PSA and BMI. However studies which have been conducted in symptomatic patients have shown a correlation between PSA and BMI. This may result from PSA level above 10 and leading to the ambiguity that it is perhaps due to high levels of PSA.