A Case Report of C3 Glomerulopathy

Complement component 3 glomerulopathy (C3G) defines a group of newly classified disorders that is due to C3 deposition in glomeruli. Very few outbreaks of this disease have been reported in the world. In this study, a 56 year old woman is reported who had complaints of weakness, abdominal pain, and skin petechiae and purpura. Laboratory tests revealed mild anemia and high serum creatinine level. Complementary studies were performed and the patient was suspected of having some form of vasculitis, especially PAN and Henoch Schonlein. Negative differential diagnosis of the most common reviews were obtained and due to lack of response to conventional therapy including corticosteroids and endoksan, kidney biopsy was done to detect the diagnosis. The patient was diagnosed with C3G. She had loss of consciousness, severe anemia, and rectorhalgia and transferred to Intensive Care Unit but died despite therapeutic efforts.