Effect of Malathion Insecticide on Liver Tissue and Enzymes of Rutilus Rutilus Caspicus of the Caspian Sea

Malathion is an organophosphate insecticide which uses to destroy insects and pests of fruit trees, ornamental plants and agricultural corps.In the present study, effect of Malathion on liver and selected enzymes (SGOT, SGPT and ALP) was studied in Caspian Roach (Rutilusrutiluscaspicus). Four treatments with three replications were designed to carry out the survey. Four groups of experimental fish (containing 30 fish in each group) were exposed to different concentrations of Malathion. e. 0, 0.01, 0.05 and 0.1 ppm respectively for 23 days. Blood collection was done in 3rd, 13th and 23th after exposure to Malathion and also 30 days after recovery in clean water and enzymes were measured using standard kits. Also liver tissues were isolated to histological examination. Results showed that tissues of control group (0ppm) were normal and there were no damages, yet there were hepatocytes degeneration, picnotic in nuclear, hepatocytes vacuolization, vascular congestion and sinusoid congestion in liver of other groups. Tissue damages were increased in higher malathion concentration and over time. Results related to enzymes showed that there were no significant differences in SGOT of fish treated with low concentrations of malathion (0.01 and 0.05 ppm) and control group but it was increased in highest concentration (p