Comparison of anti-Mullerian Hormone average between laparoscopic and treatment with clomiphene citrate in patients with polycystic ovarian syndrome

Anti-Mullerian Hormone (AMH) has been implicated in the pathogenesis of ovary polycystic syndrome. The aim was to compare AMH average in both laparoscopic and treatment with clomiphen citrate to evaluate an ovulatory response.
This clinical trial study was administrated on ovulatory women with polycystic ovary syndrome. The patients divided undergoing laparoscopic (n=49), and receiving clomiphene citrate (n=20). Plasma AMH concentrations were measured before and 1 week after treatment and then was evaluated after 3 and 6 month as well. Comparisons of means in each group were performed using ANOVA analysis.
The pretreatment mean of plasma AMH concentrations didn’t have a significant difference between laparoscopic (6.1±4.1) and clomiphene citrate treatment (5.7±3.2) (P>0.05). After laparoscopic treatment, in women who responding to treatment, AMH level was shown a significant reduction (5.6±2.1) compared with the non-responders (9±1.3) (P Laparoscopic is successful in patients who AMH levels are lower before treatment.