Survey in parasitic infestation, Trichosomoides crassicauda in Wistar and Sprague-Dawley laboratory rat strains at a producing and breeding center of laboratory animals in Iran

Trichosomoides crassicauda is a thin nematode in the urinary bladder and renal pelvis of rats and in some cases can cause urolithiasis and tumor. This parasitic infection may have been done adverse effect on the results of research works. Therefore the study of parasitic infection in breeding center is essential. In this research in a Wistar and Sprague-Dawley strains of rat colony number of 110 adult rats of both race and sex were randomly selected and were examined after autopsy. The histopathology of bladders and so lungs were done for presence of parasite larvae. In 60 examined Wistar rats, in the 54 (37 female and 17 male) and in 50 Sprague-Dawley rats, in the 43 (31 female and 12 male) parasitic infection was found. Immature worms separately and male and female adult worms were seen together. In the uterus of female worms, the eggs containing larvae were detected. In urinary bladder of 12 rats, the cyst were observed that after unpacking, debris of worms were visible.There were no evidence of tumors in various organs and in histopathology, in many cases, the body of the parasite in tissue sections and hyperplasia and wound was observed in the bladder wall. In the lungs and renal pelvis, there were no evidence of larvae and parasites.