The alternating magnetic field and convection heat transfer implications for magnetic fluid hyperthermia- A numerical analysis

In this study, numerical simulation of the effect of hyperthermia using FePt magnetic nanoparticles with alternating magnetic field for skin cancer treatment is carried out. The numerical solution is presented to analyze bioheat transfer and magnetic induction equations, in cylindrical skin tumor situated in healthy tissue with considering evaporation and convection heat transfer. In order to show the validity of the study, the obtained results are compared with those of the studies already exist in the literature. Bioheat equation is used to predict the temperature rise in terms of characteristics of the magnetic nanoparticles, applied magnetic field and the tissue. The results reveal that nanoparticles diameter has a major effect on the temperature rise. The results also show that the temperature field in axial direction (from surface to depth) of tissue and the effects of hyperthermia decreases by increasing the convection heat transfer coefficient. In other words hyperthermia is more effective in the presence of the environmental natural convection. Moreover, the position of maximum temperature inside the tumor, varies by changing the heat transfer coefficient. Also, the amount of evaporation has a negligible effect on hyperthermia treatment.