The study effect of Ofloxacin antibiotic on The diameter of seminiferous tubules In male rats & Therapeutic effect of Royal jelly on it

Ofloxacin is one of fluoroquinolone family That On infectious diseases of the urinary tract - Genital acts .R jelly is secreted by the glands of worker bees Hypopharyngeal and with impact on the reproductive, sexual orientation increases. Since antibiotics are effective in reducing fertility and are one of the factors infertility and in this study is to investigate the effects of this drug on the diameter of seminiferous tubules and Therapeutic effect of royal jelly on it . This study has been used from32 adult male rats have been divided in 4 groups .(1)control , (2) medicine ,(3) 2week without medicine, (4)R jelly . in the first group they feed only water & food stuffs , but in the 2 &3& 4 group they were received 0/3 cc ofloxacin with dose 200mg in a 14-day cycle then after the end of 14-day cycle the second group were killed the fourth group in addition to the 14-day cycle were treated for 14 days with R jelly ( dose 0/3cc) ( 28days ) Group 3 after a 14-day cycle of medication, for 14 days without medication were ( 28days) . Then the groups 3 & 4 after the end 28days were killed and exiting testis tissue and coloring with H&E .
The study showed that Ofloxacin significantly decreases diameter of the seminiferous tubules compared to controls but Royal jelly has a therapeutic effect of induction partial remission .