Relationship between Helicobacter Pylori CagA+ Infection and Iron Deficiency Anemia in Children under 5 Years of Age
Author(s):
Abstract:
Background and
Purpose
Iron anemia deficiency and helicobacter pylori infection are common diseases throughout the world. The aim of this study was to evaluate the association between iron deficiency anemia (IDA) and H. pylori CagA infection among children under 5 years of age.Materials And Methods
An analytical-descriptive study was performed in Hajar and Kashani hospitals in Shahrekord, Iran, 2014. We investigated the seropositive prevalence of H. pylori CagA infection in 59 children with IDA and compared the results with that of 69 sex- and age-matched non-anemic children using SPSS V.20.Results
The mean age of participants in case and control groups was 42±3 and 40±2 months, respectively. The controls and cases included 30 boys and 29 girls and 30 boys and 39 girls, respectively. In anemic children 50% were found to be positive for IgG anti-CagA while in non-anemic group 8% were detected. The results showed significant relationship between the two groups (PConclusion
Helicobacter pylori infection may induce iron deficiency anemia and CagA virulence factor may play a role in the severity of anemia.Keywords:
Language:
Persian
Published:
Journal of Mazandaran University of Medical Sciences, Volume:26 Issue: 144, 2017
Pages:
362 to 366
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