Application of tin oxide- inverse spinel zinc stannate nanocomposite modified carbon paste electrode for the voltammetric determination of pyridium in pharmaceutical and biological samples

The SnO2-Zn2SnO4 nanocomposite was successfully prepared via a simple solid state method. The resulted nanocomposite was characterized by field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR). Then, a novel pyridium sensor has been developed based on SnO2-Zn2SnO4 nanocomposites modified carbon paste electrode (SnO2-Zn2SnO4/CPE). The fabricated sensor exhibits outstanding electrocatalytic activities toward the oxidation of pyridium. The oxidation peak current was proportional to the concentration of pyridium from 0.3 to 607.0 µM with a detection limit of 0.009 µM at signal to noise ratio of 3. The proposed method was examined as a selective, simple and precise method for voltammetric determination of pyridium in real samples with satisfactory results.