Effect of feeding diets containing ethanol extract of algae, Sargassum angustifolium on some blood and immune factors in Macro (Labidochromis caeruleus)

It seems that the natural immune stimulants such as herbal extracts containing carotenoids, especially algae, is the most practical method to prevent fish disease.
Immune stimulants by enhancing the innate immune system can prevent the occurrence of infectious diseases. Dietary with carotenoids, has improved the immune system in many laboratory animals. In order to investigate the effect of alcoholic extract of Sorgassum angustifolium, 120 pieces of fish were randomly divided into four groups (each aquarium containing 30 piece fish, 6.5 ±0.65gr) and for 60 days for doing the experiment were maintenanced and fed. The fourth treatment was the control group that only received commercial food (Biomar) was coated with olive oil. First, second and third groups were fed with of 5, 10 and 15 g/kg ethanol extract S. angustifolium for two months. After 60 days, the fish were anesthetized and blood samples were taken for hematological and immunological studies. Among the different treatments, the highest rate of PCV, Hb and MCHC was observed in treatment that fed 5g/ kg algae (p0.05). NBT activity in the serum of treatment fed with 15g/kg S. angustifolium algae was more than the other treatments and the control group (p0.05). According to the results of the present study, oral administration of ethanol extract of S. angustifolium stimulate some nonspecific immune factors in Macro fish.