The effect of computerized cognitive rehabilitation on working & prospective memory function in Multiple Sclerosis patients

Multiple sclerosis (MS) is a demyelinating disease of the CNS that due to cognitive impairment, can reduce the quality of life in these patients. The aim of this study is to evaluate effect of computerized cognitive rehabilitation on prospective & working memory function in Multiple Sclerosis patients. 46 MS patients aged 20–40 who have the inclusion criteria, were randomly assigned to experimental and waiting-list control groups. Experimental group trained for 12 session with a Memory rehabilitation software and waiting-list control group did not receive any intervention and training of this group was postponed after conducting research. Daneman and Carpenter's capacity working memory and Retrospective-Prospective Memory Scale was applied at pretest, posttest, and follow-up. The results of repeated measures ANOVA showed a significant difference between the means of working memory in experimental and waiting-list control groups. Also, the results of the present study indicate that a significant difference between the means of prospective memory in experimental and waiting-list control groups. Moreover, the post-test and follow-up scores in the experimental group was not statistically different. So Computerized cognitive rehabilitation have significant effect on prospective and working memory performance in patients with Multiple sclerosis and it can be used as an effective and helpful method to improve memory performance of these patients.