Comprehensive Study of Clinical and Laboratory Findings in Patients with Tuberculosis

Background and Tuberculosis (TB) is an infectious disease that is lethal in many cases. The aim of this study was to evaluate the clinical and laboratory findings in patients hospitalized with tuberculosis.
A cross-sectional study was carried out in 61 patients with tuberculosis in Razi Qaemshahr Hospital , Iran 2014-2015. We compared paraclinical and clinical findings in patients, those who died, individuals with recurrent TB, and patients with underlying diseases. Data was analyzed in SPSS V19. All P values less than 0.5 were considered significant.
Significant differences were seen in ALP, RBC count, and hemoglobin in patients who had relapsed serum and new cases. Also, there were significant differences between alive and dead patients in levels of ALT, ALP, PPD, FBS, and creatinine levels. The HCT level, FBS, RBC, MCHC, platelet count, and serum ferritin differed significantly in patients who were HIV-positive and negative. Moreover, we found significant differences in MCV, WBC, MCH, MCHC, and AST between TB patients with and without liver disease. In TB patients with and without diabetes the levels of ALT and BS were significantly different.
Comparison of paraclinical outcomes in TB patients with and without underlying diseases, proves the importance of early diagnosis of clinical disorders in these patients. Therefore, elimination of these causes can lead to faster recovery and better treatment response in these patients.