The effect of Iranian and foreign Infectious Bursal Disease vaccines on humoral immune response against Newcastle and Influenza vaccines in broiler chicks

In order to study the effect of foreign and Iranian intermediate Gumboro vaccines on immune response against Newcastle and avian influenza vaccines , three hundred and thirty day-old chicks were purchased and for determination vaccination time, thirty chicks randomly were bled and remaining chicks divided into 3 equal groups and each group divided into 4 equal subgroups. On the basis of ELISA results and vaccines instruction, chicks of group 1 was vaccinated by intermediate Gumboro vaccine including strain LC75, manufactured by Lohman Germany company and chicks of group 2 was vaccinated by intermediate Gumboro vaccine (07IR) , manufactured by Razi vaccine and serum research Institute of Iran at 16 and 23 days by drinking water. One group was kept as unvaccinated control group. At 9 days old, all 3 groups were vaccinated by B1 Newcasle vaccine via eye drop and mixed killed Newcastle and avian Influenza vaccines inoculated at neck back subcutaneously. The blood samples from 16 birds of each group were collected at 42 days of age. Mean blood serum titer against Newcastle and avian influenza were measured by HI test. This study showed that administration of foreign and Iranian intermediate Gumboro vaccines in ages higher than 2 weeks old, had no negative effect on immune response against Newcastle and avian influenza vaccines.