The effect of combined training on body composition, and ccoagulation and proinflammatory factors in overweight and obese postmenopausal women

Research suggests that the decline in ovarian function with menopause is associated with spontaneous increases in pro inflammatory and coagulation factors. The aim of this study was to determine the effect of combined training on body composition, and inflammatory and coagulation factors in overweight and obese postmenopausal women.
In this quasi experimental study, a total of twenty-six apparently health postmenopausal women were randomly assigned to an endurance resistance exercise (n = 13) or control group (n = 13). The exercise group trained 90 minute, three times per week for 8 weeks. The control group did not train. End points included changes in weight, body mass index (BMI), waist-to-hip ratio (WHR), and serum high sensitive C-reactive protein (hs-CRP), interleukin 6 (IL-6), and plasma fibrinogen between baseline and 8-th week. Data were analyzed by paired and independent t test. P-value Twenty-two participants completed the trial. At baseline, there were no significant differences in study variables between control and exercise groups. Exercise training significantly reduced weight, BMI, and WHR (p=0.001). Also exercise training decreased plasma levels of hs-CRP and IL-6 (p=0.001), and fibrinogen (p=0.01) in experimental group. While the control group showed no significant changes during this period.
Our study showed that exercise training is effective in reducing body composition and inflammatory and coagulation factors in overweight and obese postmenopausal women. So, Our results suggest that an endurance-resistance exercise program can improve health status of postmenopausal women.