Prevalence of Chlamydia Trachomatis, Mycoplasma Genitalium and Neisseria Gonorrhea in Infertile Females Referred to Mahdieh Hospital in Tehran

Infertility rate has increased by 50% during the last two decades in Iran. There are several factors affecting infertility among women and men, amongst which infections have gained a lot of attentions recently. Given the high percentage of infertility in Iran, the present study has aimed to investigate the prevalence of Chlamydia trachomatis, Mycoplasma genitalium and Neisseria gonorrhea amongst infertile women referring to a hospital in Tehran, Iran.
In the current descriptive study, 65 infertile women referring to Mahdieh Hospital in Tehran during 2016-2017 were included and two vaginal swabs and a questionnaire were taken for each patient. In the laboratory, DNA extraction using kit and PCR using specific primers were carried out.
Of the 65 vaginal swab specimens, 21 (32%) had bacterial infection and 44 (68%) had no bacterial infections, and 2 (3%) had the mixed infection. The prevalence of C. trachomatis, M. genitalium and N. gonorrhea were 9 (13.8%), 11 (16.9%) and 4 (6.2%) isolates, respectively. There was no relationship between history of abortion, use of oral contraceptive pills, education or age, with the prevalence of bacterial infections.
Based on the results of this study, M. genitalium, N.gonorrhea, and C.trachomatis were quite prevalent among infertile females and it can, therefore, be concluded that on-time control and treatment of infections caused by these organisms, together with other factors, could be important in prevention and treatment of women's infertility and the community’s health.