Evaluation of Antibacterial Activity of Iron Oxide Nanoparticles against Escherichia Coli

Article Type:
Review Article (دارای رتبه معتبر)
Abstract:
Background
Due to the useful applications of metal oxide nanoparticles in medicine, in this study iron oxide nanoparticles were biosynthesized using bioresource to evaluate its antibacterial activity against Escherichia coli.
Methods
The iron oxide nanoparticles were synthesized using bioresource as previously described. Macrodilution method of calculating the lowest concentration prevent the growth of bacteria (MIC); also, the lowest concentration that destroyed all bacterial cells were calculated (MBC).
Results
The lowest concentration of iron oxide nanoparticles that inhibited the growth of E. coli considered as a minimum inhibitory concentration (MIC) was recorded at the concentration of 250 µg/ml, but the minimum bactericidal concentration (MBC) of iron oxide nanoparticles was calculated at the concentration of 500 µg/ml.
Conclusions
The iron oxide nanoparticles were synthesized by green and eco-friendly, simple and inexpensive method. The biogenic iron oxide nanoparticles have impressive antibacterial properties. The results showed the inhibitory effect of the iron oxide nanoparticles of E. coli at 250 µg/ml. The iron oxide nanoparticles are effective antibacterial agents.
Language:
English
Published:
International journal of basic science in medicine, Volume:2 Issue: 4, Dec 2017
Pages:
166 to 169
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