The Effect of Probiotic Supplementations on Cognitive Function in Patients with Primary and Secondary Alzheimer

Author(s):

Azadeh Agahi , Gholamali Hamidi * , Mahmoud Salami , Azam Alinaghipour , Reza Daneshvar Kakhaki , Masoud Soheili

Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background
Alzheimer’s disease (AD) is a most common neurodegenerative disorder. The aim of this study was to investigate the effect of probiotic on cognitive function in patients with Alzheimer disease.
Materials And Methods
This clinical trial was conducted among 48 AD patients. The patients were randomly divided into two groups (n=23 in control group and n=25 in probiotic group) treating with capsules 500mg containing maltodextrine (control group) and probiotic supplementation (probiotic group) for 12 weeks. Mini-mental state examination (MMSE) and TYM test score was recorded in all subjects before and after treatment.
Results
After 12 weeks intervention, compared with the control group, the probiotic treated, patients with mild degree of Alzheimer disease showed an improvement in the MMSE, TYM score (p
Conclusion
Our current study demonstrated that probiotic consumption for 12 weeks positively affects cognitive function in mild degree of AD.
Keywords:

Alzheimer , Cognitive function , Probiotic

Language:
Persian
Published:
Journal of Arak University of Medical Sciences, Volume:20 Issue: 12, 2018
Pages:
1 to 9
https://www.magiran.com/p1793869  
سامانه نویسندگان
  • Hamidi، Gholam Ali
    Corresponding Author (2)
    Hamidi, Gholam Ali
    Professor Department of Physiology, School of Medicine, Kashan University Of Medical Sciences, کاشان, Iran
  • Daneshvar Kakhki، Reza
    Author (5)
    Daneshvar Kakhki, Reza
    Assistant Professor neuyrology, Kashan University Of Medical Sciences, کاشان, Iran
اطلاعات نویسنده(گان) توسط ایشان ثبت و تکمیل شده‌است. برای مشاهده مشخصات و فهرست همه مطالب، صفحه رزومه را ببینید.
مقالات دیگری از این نویسنده (گان)