Investigation of relationship between the C825T polymorphism in GNB3 gene and obesity in the population of Ardabil, Iran

Obesity is currently a risk factor for many diseases and health problems that one of the main causes of its incidenceare genetic factors. One of the genetic factors that recently considered for obesity is polymorphisms of GNB3. This study aimed to investigate the association between C825T polymorphism in GNB3 with obesity in the population of Ardabil. In this case-control study, 100 obese subjects (case group) and 100 healthy subjects (control group) were included basis of their body mass index. 42% of healthy and 44% of obese subjects were male, and 58% of healthy and 56% of obese subjects were female (P = 0.775). The mean age of healthy and obese subjects was 41.5±16.7 and 41.6±13.8, respectively (P