Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt's Striae: A Contralateral Eye Study

The aim of this study was to evaluate and compare topographic characteristics in bilateral keratoconus (KCN) patients with unilateral Vogt’s striae.
In this prospective cross-sectional contralateral eye study, the KCN patients that were enrolled in this study had a reliable diagnosis of bilateral clinical KCN with unilateral Vogt`s striae based on slit-lamp signs, as well as corneal topographic/tomographic maps. All the cases underwent a comprehensive ophthalmic examination, including uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA),cycloplegic refraction (calculated by vectorial analysis), and placido disc-based Tomey topographer (TMS-4; Tomey, Germany). In this study, clinical and topographic characteristics of all cases were evaluated and compared between the contralateral KCN eyes with Vogt`s striae and those without Vogt`s striae. Paired sample t-test was used to compare the parameters with a normal distribution and the Wilcoxon signed rank test was used to compare the non-parametric parameters. P-value Fifty patients aged 20 to 38 years (27.43±5.46) were recruited in this study. Our results showed that there were significant differences in sphere, cylinder, spherical equivalent, UDVA, CDVA and J0 (all p Corneal topographic parameters showed a significant difference between the contralateral KCN eyes with and without Vogt’s striae. These results should be noticed in clinical evaluations and treatments of KCN patients.