Rare case of bilateral vassal agenesis and AZFc microdeletion: A case report

Article Type:
Case Report (دارای رتبه معتبر)
Bilateral vassal agenesis (CBAVD) is a rare cause of male infertility. Also one of the
nonobstructive cause of azoospermia and infertility in men is microdeletion in long arm of Y chromosome.
In this case report we have reported a rare case of CBAVD, LT renal agenesis and AZFc
microdeletion. Patient Information: 28 years old man, who was farmer with history of 6 years of infertility presented to our andrology
clinic in Royan institute. In physical examination there was not any palpable vas deferens bilaterally,
also The semen analysis was azoospermia. In sonographic evaluation, LT kidney wasn’t seen in
its anatomic location. The patient candidate for diagnostic PESA and bilateral PESA were negative.
After that, the patient candidate for bilateral TESE and fascinatingly TESE was negative too. After
genetic evaluation microdeletion was detected in AZFc subregion of Y chromosome.
In men with obstructive azoospermia mostly testicular spermatogenesis is normal but this is not
the rule because seldom spermatogenic dysfunction maybe present like our patient. We emphasize
about the importance of consideration of obstructive and nonobstructive azoospermia together in
a patient for urologists.
Men's health journal, Volume:2 Issue: 1, Winter 2018
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