A Study On The Relationship between Total Salivary Antioxidant Level and Periodontal Disease

Increase in free radicals leads to oxidative stress which is implicated in the pathogenesis of many systemic and oral diseases such as periodontal disease. The aim of this study was to find the relationship between the salivary total antioxidant level and periodontal disease.
Subjects and This case control study included 15 patients with periodontitis, 15 patients with gingivitis and 15 controls were recruited from patients referring to Ahwaz Dental School in 1390-1391. The levels of salivary total antioxidants were evaluated using Spectrophotometry method. Control group had significantly higher total salivary antioxidant level compared with patients with gingivitis and periodontitis (P<0.001).The difference between total salivary antioxidant level in patients with gingivitis and periodontitis was not significant (P>0.05). The findings demonstrate an inverse relationship between total antioxidant level with development of periodontitis and gingivitis