Demographic and Clinical Characteristics of Guillain-Barre Syndrome (GBS) in Patients Referring to Farshchian Hospital of Hamadan during 2006- 2015

Guillain-Barre syndrome is an autoimmune neurological disease that is considered as the most serious type of paralysis without reflex. Different factors and therapeutic measures are effective in causes and how to control it. The aim of this study was to determine the epidemiology of Guilen Barre syndrome in Hamedan province during the years 2006-2015. In this cross-sectional descriptive study the required information from the records of 159 patients admitted to hospital Farshchian Hamadan, was investigated over a period of 8 years. The relationship between variables was analyzed by SPSS software version 16 using chi-squared test and independent T-test. Of the 159 patients, 58 (40.8%) were female and 98 (61.6%) were married. The mean age of patients was 48 ± 22.6. Lower limb weakness (95%) was the most common symptom and difficulty in swallowing and respiratory distress had the lowest incidence of symptoms. The largest age group of patients with Guillen-Baar syndrome was between the ages of 21-30. Relative healing was observed in 43 cases (27%) and death was observed in 15 cases (9.4%). There was no statistically significant relationship between gender, age, and marital status with symptoms appearing in patients with Guillen-Baar syndrome. The results revealed a different pattern of the epidemiology of Guillain-Barre syndrome in Iran from other countries. So different environmental factors are involved in GBS. According to disability and even death in such GBS patients, further research to find the etiology, treatment and prevention services will be required.