The Anti–Inflammatory Effect of High Intensity Interval Training in Overweight Women with Type 2 Diabetes

Diabetes mellitus and chronic inflammation are strongly related to increase cardiovascular risk. It is well documented that diabetic patients are 2-4 times more likely to suffer from cardiovascular diseases than healthy individuals. The study aimed to determine the effect of high intensity interval training (HIIT) on fat mass and inflammatory factors in overweight women with type 2 diabetes.

twenty patients with
type 2 diabetes were assigned to control and exercise group. Exercise group performed HIIT (running on treadmill) 6 weeks (3 session/week). Blood samples were collected before first session and 24 hours after the last exercise session and used for measurement by ELISA methods.

The results of independent t-test of groups showed significantly decrease in fat mass and TNFα levels in exercise group compared with control group (p <0.05) whereas IL-6 reduction was not statistically significant.

The results of this study showed that HIIT can be a key factor in decreasing of fat mass and inflammatory factors in overweight women with type 2 diabetes.