Epidemiologic Assessment of Odontogenic Keratocyst in Patients referred to Taleghani Hospital, Tehran, 1991-2002

The purpose of this study was to report our experience in the diagnosis, surgical treatment and follow up of 27 Iranian patients. Method & Materials: A retrospective analysis was conducted of odontogenic keratocyst that were diagnosed and treated between 1991-2002.Clinical and histologic data were complied from the patient records and pathologic reports. Including recurrences and syndromic types, the material comprises 37 OKCs. The man: woman ratio was 2.375:1 and most of the patients belonged to the age groups 20-29 (%29.7) and 10-19(%18.5). %83.8 of the OKCs were localized in the mandible. The most common site was the third molar, angle and Ascending ramus area. The most frequent clinical manifestation at first admission were swelling (%77.7), pain (%63), purulent discharge (%48.1) and neurologic involvement (%14.8). Radiographic impressions included unilocular pattern (%68.8) and multilocular pattern (%31.2). The diagnosis of Gorlin's syndrome was established in two patients (%7.5). Recurrences were observed in 5 patients and the mean time interval between the primary operation and the first recurrence was 3 years. Half of the cases were treated with enucleation and corettage,%36 with enucleation and peripheral ostectomy,%8 with marsupialization and %5 with partial resection.Parakeratosis and ortho-and parakeratosis was observed in %94.6of the cases and orthokeratosis in %5.4.Malignancy was observed in one case. In our study, most features of OKC are consistent with those previously reported.