The comparison of antibacterial and antifungal effects of Pistacia atlantica gum with some inuse antibiotics.

According the known side effects of using some antibiotics and the results of antibacterial and antifungal compounds in Pistacia atlantica, in this research antibacterial and antifungal effects of Pistacia atlantica were compared with common antibiotics. After collecting gum of pistacia atlantica in habitats(Lorestan province, Kohdasht city), its antimicrobial effects on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans and Candida glaberata was investigated by disc diffusion method and MIC, MBC, MFC were determined. The data were analyzed by t-test and one-way ANOVA variance. Among the bacteria, the most diameter of the inhibition zone at a concentration of 5 mg/ml is related to Staphylococcus aureus (more than amikacin and less than Vancomycin) and the least diameter of the inhibition zone at a concentration of 0.156 mg/ml is related to pseudomonas aeruginosa. The lowest levels of MIC and MBC were 5.312 and 625 μg/ml, respectively for Staphylococcus aureus. Among the fungi, the most diameter of the inhibition zone at a concentration of 5 mg/ml is related to Candida albicans (less than fluconazole and nystatin) and the least diameter of the inhibition zone at a concentration of 0.156 mg/ml is related to Candida glaberata. The lowest MIC and MFC related to C. albicans were 625 and 1250 μg/ml, respectively. It seems that pistacia atlantica gum has a stronger antibacterial activity rather than some tested antibiotics.