The effect of sublethal doses of endosulfan on hematological, biochemical factors and immunity of mucus in roach (Rutilus caspicus)

According to the importance of roach as a valuable species in Caspian Sea and the entrance of toxin to the sea, the aim of this study was to investigate the effect of endosulfan toxicity on mucus immunity and hematological factors in Rutilus caspicus. So, after determining the LC50 for this species, 20 fish with the average weight of 18.46±2.32 g were exposed to 10% and 20% LC50 for 21 days. Samples from mucus and blood were performed on days 1, 7, 14 and 21. At the end of the experiment, the results showed that total protein and IG had the highest levels in 20% endosulfan in 21 day and there were significant differences between 20% and control (P<0.05). Although hemoglobin, hematocrit and red blood cells decreased when the dose of endosulfan and time exposed to it increased, the number of white blood cells increased. The most of Hb, Ht and RBC were in the control group, which had a significant difference with other treatments (P<0.05). In general, it can be concluded that exposure to endosulfan stimulates the non-specific immune system of the Rutilus caspicus.