Histopathology of gallbladder lesions of confiscated livers from cattle slaughtered in urmia abattoir

During one month carcasses of 323 cattle (213 bulls and 110 cow) were inspected by referring to Urmia slaughter-house. Livers and gallbladders of 47 cattle had macroscopic changes. Histopathologic sections were prepared from injured tissues and for bacteriology, contents of injured and normal gallbladders were cultured. Major macroscopic changes that were observed in damaged livers and gallbladders were: increasing of gallbladder thickness, petechiae, choleliths in gallbladder, hepatolithiasis, hepatic fascioliasis and presence of dicrocoelium in gall bladder. Histological sections were stained by hematoxylin and eosin, periodic acid schiff and masson’s trichrome staining methods. Cholecystitis, hyperplasia of seromucosal glands’ congestion, hemorrhage, fat necrosis and increased thickness of gallbladder layers were observed. Also Escherichia coli was isolated from 4 gallbladders. In females, the incidence of microscopic changes including cholecystitis, increasing of mucosal layer thickness, hyperplasia of seromucosal glands, hemorrhage in layers except the mucosal layer and presence of bacteria in culture of gallbladder contents was more than males (p<0.05). Also incidence of cholecystitis in native breeds was more in comparison with hybrid and Holstein breeds (p<0.05). According to the results, prevalence of hepatic fascioliasis is a predisposing factor for cholecystitis in this area. Also traditional feeding and diet regimen of native cattle are effective in creation of cholelithiasis which arise as a result of cholecystitis.