Application of Advanced Nanomaterials in Enzyme Biosensing Technology

The application of enzymes in biosensors are common since the enzyme acts highly specific and possess catalytic properties. For the development of enzymatic sensor, the selected enzyme required to be immobilized and fixed on the surface of probe or transducer by the desired method such as absorption, entrapment, covalent binding, cross-linking, bio-affinity, etc. In order to accelerate electron transfer and enhance enzyme catalytic activities, some of the nanomaterials such as carbon nanotube, graphene, noble metal nanoparticle, and silica nanoparticles can be used for immobilization of enzymes. In this study, the application of advanced nanomaterials in enzymatic biosensor was discussed. Also, some of the advantages and challenges in nanomaterial-based enzyme Nano-bio sensors were discuses.