Effects of toxin binder BIOTOX on productive performance and health status in Holstein cows

In order to evaluate the effect of bi-partial toxin binder "Biotox" on health status and productive parameters, sixteen Holstein cows were classified into two groups, biotox (supplemented with Biotox) and control (without Biotox). Feed intake, dry matter intake, body weight, body condition score, rectal temperature, respiratory rate, heartbeat, milk yield and compounds and blood parameters were measured and recorded. In control group feed intake, dry matter intake, body weight and body condition score were significantly decreased from forth to seventh week, while rectal temperature, respiratory rate and heartbeat were increased (P≤0.05) during the entire period. The milk yieldincreased non-significantly during the entire period and significantly (P≤0.05) from fifth to seventh week in biotox group. Content of milk protein (P≤0.05) in biotox group and percent of fat (P≤0.05), percent of lactose (P≤0.05), somatic cell count and concentration of aflatoxin M1 (P≤0.05) in control group were increased. Milk solids content in the biotox group increased non-significantly during the entire period and significantly in the fifth to seventh week (P≤0.05). There were no significant difference in concentration of plasma glucose, total protein and creatinine during the entire period, but in control group, creatinine level increased during the late period. Plasma aspartate transaminase (P≤0.05) and alanine aminotransferase (P≤0.05) were higher in the control group. Overall, biotox use improves the health, milk production, and production parameters of lactating cows when the feed is exposed to multiple mycotoxin contamination.