Safety and efficacy of antimicrobial nanostructured textiles: comparison with 11070 national standard

Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background

This study aimed to evaluate the efficacy and safety of five randomly selected nanostructured products by the National Standard of No. 11070.

Materials and methods

Antibacterial activities of five different nanostructured textiles were assessed on specific microorganisms to human skin and environment. The physicochemical properties were determined by FTIR spectrum and the dermal toxicity was assessed by skin and eye irritation and corrosion test (OECD 404,405).

Results

Each of the 5 samples at concentrations of 0, 0.5, 1, 1.5, 2 and 5% had strong antibacterial activity compared to control treatments. Mild and reversible irritations were observed at all three concentrations of nanosilver (5, 50, and 500 ppm) after 24 hours exposing to yarn and tissue samples on female rabbits, and the FTIR test related to 5 products showed no change in group, before and after the treatments e.g. washing and contact with the test animals (rabbits). Tissues containing nano-silver particles had no irritating effect and eye lesions in rabbits.

Conclusion

According to the results, in addition to complying with the properties mentioned in the health license, the nanostructured textiles complied with the standard features of 11070.

Language:
Persian
Published:
Medical Science Journal of Islamic Azad Univesity Tehran Medical Branch, Volume:30 Issue: 2, 2020
Pages:
174 to 184
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