Comparison of the effect of oral Meloxicam to paracetamol and Sufentanil on analgesia after cesarean section

Due to the importance of pain control in the postoperative period, the use of pain killers reduces postoperative complications by improving the patients’ pain intensity. This study was performed to compare the efficacy of oral Meloxicam with pain pump containing Paracetamol and Sufentanil in post-cesarean analgesia.

In this clinical trial study, 59 pregnant women undergoing spinal cesarean section in Ali ebn-e Abi taleb Hospital of Zahedan in 2017 were studied. Patients were randomly divided into two groups receiving oral Meloxicam and Paracetamol and Sufentanil pain pump. The severity of pain, satisfaction, sedation and need for analgesics were assessed in both groups.

Mean age of patients was 26.9 ± 4.9 years. In the present study, mean pain intensity in patients receiving Meloxicam and pump at zero moment were 3.9 ± 1.5 and 4.2 ± 1.4 (P = 0.426), at 6 hours post-surgery, respectively  3.3±0.9 and 2.6 ± 0.8 (P = 0.006) ,at 12 h post-surgery  were 2.1 ± 0.9 and 1.7 ± 0.7 (P = 0.059) and at 24 h, respectively were 1.0 ± 7.8 and 1.1 ± 0.7, respectively (P = 0.001) .The need for analgesic in Meloxicam  group was 18.1 ± 11.4 mg and in pain pump group was 10.8 ±12.6 mg. (P = 0.024).

The results of this study showed that pain intensity in patients receiving pain pump was significantly lower than those taken oral Meloxicam. Also, the demand for analgesic was lower in this group.