Study on biological distribution of a gallium-67 radionuclide labeled porphyrin complex grafted on functionalized MCM-41 nano silica as a nuclear imaging agent
Nowadays, aminopropyl functionalized mesoporous silica MCM-41 is known as a potential anticancer-drug delivery system with a high surface area. In this work, so as to produce an image-guided drug delivery system for diagnostic applications, proto porphyrin was radiolabeled with 67Ga radionuclide and this complex was grafted on 3-aminopropyl functionalized MCM- 41. The nanoparticles were assessed with radio thin layer chromatography RTLC, X-ray diffraction, FTIR spectroscopy, surface area analysis BET and ThermogravimetrY.
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