The Effect of Aerobic Training on Lipid Accumulation Product, Visceral Adiposity, Triglyceride-Glucose and Mcauley Indices in Early Pubertal Obese/Overweight Girls

By considering the growing trend of obesity, along with metabolic disorders among children, especially insulin-resistance (IR), the present study aimed to evaluate the effect of aerobic-training on the levels of spexin, lipid-accumulation product (LAP), visceral-adiposity (VAI), triglyceride-glucose (TyG) and McAuley indices among early-pubertal obese/overweight-girls. 32 obese/overweight-girls (age 9.62±0.75 years-old, weight 49.71±9.26 kg, BMI 25.40±2.92 kg/m2, Tanner-stage 2-3) voluntarily participated in this study, who were assigned into interval-walking (n=12), continuous-walking (n=11) and control (n=9) groups. The subjects were trained three-times/week for two-months (30-min walk in the continuous and interval-groups with 60-75%HRmax and 70-85%HRmax, respectively). Spexin concentration was measured by ELISA method, and visceral-adiposity and IR indices were calculated according to the equations. Factorial repeated-measured ANOVA was used for data analysis. Based on the results, the interaction-effect of time×group was statistically significant for the LAP (P=0.007), VAI (P=0.045), McAuley (P=0.026) and TyG (P=0.001), while it was insignificant for the spexin (P=0.836). Regarding the control group, the LAP, VAI, and TyG significantly increased (P=0.037, P=0.046, P=0.005, respectively) while a significant decrease happened for McAuley (P=0.030). In the continuous-walking group, a significant decrease was observed in LAP (P=0.002), and TyG (P=0.002), while VAI and McAuley levels tended to decrease (P=0.057) and increase (P=0.071), respectively. In the interval-walking group, there was insignificant change in the LAP, VAI, TyG, and McAuley (P=0.129, P=0.660, P=0.390, P=0.357, respectively). The findings showed that the continuous-walking for eight-weeks could reverse the increase in visceral-adiposity and IR indices in the control group, irrespective of the changes in serum levels of spexin.