The role of cognitive functions, gratitude and depression in predicting quality of life in patients with multiple sclerosis (MS)

The aim of this study was to investigate the role of cognitive functions, gratitude and depression in predicting the quality of life in patients with multiple sclerosis (MS). This cross-sectional study was performed on 92 patients referred to the physiotherapy section of the MS Society of Tehran. Data were collected using the Cognitive Functioning Questionnaire (Nejati, 2013), the Quality of Life Questionnaire (World Health Organization, 1996), the Gratitude Questionnaire (McCluff and Whiteley, 2002) and the Depression Questionnaire (Beck et al., 1961). The data were analyzed by multiple regression and Pearson correlation coefficient using spss.23 software. The results of correlation coefficient showed that the variables of cognitive functioning (r = 0.438), depression (r =- 0.303) and gratitude (r = 0.467) had a significant relationship with quality of life (p <0.05). Regression results also showed that 51.4% of the variance in quality of life is explained by cognitive functions, gratitude and depression. So although people with MS may experience depression, the high gratitude of individuals may allow individuals to appreciate individuals, events and situations in life and be appreciative of their lives and social relationships.