Nasopharyngeal Metastasis Originating From Beta-HCG Being Secreting From Transitional Cell Carcinoma of the Renal Pelvis: A Case Report

Transitional cell carcinomas (TCC) of the upper urinary tract constitute only 7% of urothelial carcinomas. The majority of upper urinary tract TCC arises from the renal pelvis, followed by the ureter. The majority of the patients are presented with microscopic or macroscopic haematuria, flank pain, or symptoms due to metastasis; however, it can be asymptomatic in 10-15%.

Here, we report the case of a 58-year-old male who was referred with headache and cranial nerve palsy, later diagnosed with beta-human chorionic gonadotropin (beta-HCG) that was secreted from TCC of the renal pelvis with nasopharyngeal, lung, and brain metastasis.

Nasopharyngeal metastasis from TCC of the renal pelvis is a rare entity and this case report adds to the present literature.