Identify the short-term effects of exposure thermos-hygrometric stress on embryonic development

Heat-humidity stress is one of the most important environmental factors affecting the development of the fetus and the health of pregnant maternal., Studies in this area have been limited. The aim of this study was to investigate the effects of short-term exposure to heat-humidity stress in the form of THI on fetal growth and development. For this purpose, animal models were used...  pregnant NMRI mice that were exposed to heat-humidity stress in the chamber during the second period of pregnancy (3, 5, 8, 10 and 15 minutes) daily for short periods Placement courses (GD 14.5-17) is designed in accordance with the growth and development of the human embryo. Exposure to thermal-humidity stresses in the second period (GD6.5-14) during of pregnancy shows an increase in maternal mortality and fetal weight loss, crown-to-rump length (CLR) and placental weight in comparison with the control group. Also, with increasing thresholds of stress at different thresholds of the index, embryonic abnormality (Exohatics, Facial Deformity, C-Shaped Body, Ear structure defects, Hemangioma and Limbic Adhesion) have increased. T-test of two independent samples and ANOVA confirmed the above-mentioned results at the level (p-value<0.01). The results of this study can be effective in the development of care programs, treatment and education of pregnant mothers, and to monitor the thermal stresses and design of warning systems.