Evaluating diagnostic accuracy of Ovarianinstantfrozensections compared to delayed paraffin embedded permanentsections

Frozen section is mainly performed to determine malignity, so it is of fundamental importance to evaluate the diagnostic accuracy of frozen sections performed for each group of tissues in order toreduce false diagnoses, unnecessary surgeries and followingunwanted complications. This study is conducted to evaluate the diagnosticaccuracy of frozen section performed on ovary tissue compared to permanent sections.

In this retrospective study, we evaluate frozen sections performed at Taleghani hospital pathology department in five yearsandtheir results were compared with permanent sections’ results to calculate sensitivity, specificity, negative predictive value and positive predictive value. In cases which results were discordant,we check for probable reasons.

83species were evaluatedfrom patients with a mean age of 42.9 years; the smallest was 19 andthe oldest was 86 years old(Std. dev: 12.84). 75cases of frozen sections were benign(90.4%) and8 cases were malignant. 73cases of permanent sectionswere benign(88%) and10 cases were malignant(12%. Sensitivity, specificity, positive predictive value and negative predictive value rates were 66%, 100%, 100% and 96.55% respectively.

This study shows the importanceof cooperation between pathologist and surgeons that they can prevent unnecessary surgeries. Inour study the only cases of discordancy were borderline tumorsandthe diagnostic accuracy for all other species were perfect.